AccScience Publishing / HPR / Online First / DOI: 10.36922/HPR026080043
RESEARCH ARTICLE

Meaning in life moderates the association between pain catastrophizing and mental quality of life in older adults with chronic pain: A cross-sectional study

Mariko Horii1,2* Takeshi Hatta3 Satoshi Shimai3 Akihiko Iwahara4
Show Less
1 Department of Education, Graduate School of Faculty of Human Development and Education, Kyoto Women’s University, Kyoto, Japan
2 Medical Corporation Souwakai, Otsu, Shiga, Japan
3 Department of Health Sciences, Faculty of Health Welfare, Kansai University of Welfare Sciences, Kashiwara, Osaka, Japan
4 Department of Psychology and Collaboration, Faculty of Psychology and Collaboration, Kyoto Women’s University, Kyoto, Japan
Received: 17 February 2026 | Revised: 25 April 2026 | Accepted: 11 May 2026 | Published online: 29 May 2026
© 2026 by the Author(s). This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC-by the license) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Background: The burden of chronic pain is high among older adults and is associated with a reduction in health-related quality of life (HRQOL). Pain catastrophizing is a key psychological factor that exacerbates pain-related distress; however, the role of the meaning in life (MIL) in this relationship remains unclear.

Objective: This study aimed to examine whether the MIL, a key construct in positive psychology, moderates the relationship between pain catastrophizing and HRQOL among older individuals living with chronic pain.

Methods: A cross-sectional online survey was conducted targeting adults aged ≥ 65 years with chronic pain. Of the 400 respondents, 349 (177 women, 172 men) met the inclusion criteria and were included in the analysis. The study used standardized instruments: the catastrophizing scale, the Meaning of Life Questionnaire, pain intensity assessments, and HRQOL measures. Correlation analysis and multiple regression were performed, with statistical significance set at p < 0.05.

Results: MIL was identified as a moderator of the relationship between mental quality of life (QOL) and magnification (β = 0.130*). Specifically, higher levels of MIL attenuated the negative association between magnification and mental QOL. In contrast, no such moderating effect was observed for physical QOL.

Conclusion: The MIL may serve as a psychological resource that buffers the adverse impact of maladaptive pain-related cognitions on mental QOL in older adults with chronic pain. Interventions aimed at enhancing the MIL may help improve psychological well-being in this population.

Keywords
Meaning in life
Quality of life
Catastrophizing
Pain
Older adults
Funding
None.
Conflict of interest
The authors declare that they have no conflicts of interest.
References
  1. Yamada K, Fujii T, Kubota Y, et al. Prevalence and municipal variation in chronic musculoskeletal pain among independent older people: Data from the Japan Gerontological Evaluation Study (JAGES). BMC Musculoskelet Disord. 2022;23(1):755. doi: 10.1186/s12891-022-05694-y

 

  1. Golovchanova N, Owiredua C, Boersma K, Andershed H, Hellfedt K. Presence of meaning in life older men and women: The role of dimensions of frailty and social support. Front Psychol. 2021;12:730724. doi: 10.3389/fpsyg.2021.730724

 

  1. Dong HJ, Gerdle B, Bernfort L, Levin LÅ, Dragioti E. Pain Catastrophizing in Older Adults with Chronic Pain: The Mediator Effect of Mood Using a Path Analysis Approach. J Clin Med. 2020;9(7):2073. doi: 10.3390/jcm9072073

 

  1. Presto P, Sehar U, Kopel J, Reddy PH. Mechanisms of pain in aging and age-related conditions: Focus on caregivers. Ageing Res Rev. 2024;95:102249.doi: 10.1016/j.arr.2024.102249

 

  1. Afrashteh MY, Abbasi M, Abbasi M. The relationship between meaning of life, perceived social support, spiritual well-being and pain catastrophizing with quality of life in migraine patients: The mediating role of pain self-efficacy. BMC Psychol. 2023;11(1):17. doi: 10.1186/s40359-023-01053-1

 

  1. Sullivan MJL, Bishop SR, Pivik J. The pain catastrophizing scale: development and validation. Psychol Assess. 1995;7(4):524-532. doi: 10.1037/1040-3590.7.4.524

 

  1. Simic K, Savic B, Knezevic NN. Pain catastrophizing: How far have we come. Neurol Int. 2024;16(3):483-501. doi: 10.3390/neurolint16030036

 

  1. Yamin JB, Meints SM, Edwards RR. Beyond pain catastrophizing: rationale and recommendations for targeting trauma in the assessment and treatment of chronic pain. Expert Rev Neurother. 2024;24(3):231-234. doi: 10.1080/14737175.2024.2311275

 

  1. Schütze R, Rees C, Smith A, Slater H, Campbell JM, O’Sullivan P. How can we best reduce pain catastrophizing in adults with chronic noncancer pain? A systematic review and meta-analysis. J Pain. 2018;19(3):233-256. doi: 10.1016/j.jpain.2017.09.010

 

  1. Martela F, Steger MF. The meaning of meaning in life: Coherence, purpose and significance as the three facets of meaning. J Posit Psychol. 2016;11(5):531-545. doi: 10.1080/17439760.2015.1137623

 

  1. Coelho A, Lopes M, Barata M, et al. Biopsychosocial Factors That Influence the Purpose in Life among Working Adults and Retirees. Int J Environ Res Public Health. 2023;20(8):5456. doi: 10.3390/ijerph20085456

 

  1. Boylan JM, Tompkins JL, Krueger PM. Psychological well-being, education, and mortality. Health Psychol. 2022;41(3):225-234. doi: 10.1037/hea0001159

 

  1. Sutin AR, Luchetti M, Karakose S, Stephan Y, Terracciano A. Meaning in life and all-cause and cause-specific mortality in the UK Biobank. J Psychosom Res. 2025;188:111971. doi: 10.1016/j.jpsychores.2024.111971

 

  1. Fischer IC, Feldman DB, Tsai J, et al. Purpose in life and physical health in older U.S. military veterans: Cross-sectional results from the National Health and Resilience in Veterans Study. Prev Med. 2023;170:107495. doi: 10.1016/j.ypmed.2023.107495

 

  1. Vinaccia S, Castelblanco-Toro SM, Quiceno JM, Vargas MDR. Ikigai (purpose in life) and quality of life in older adults in socially disadvantaged conditions within a rural Colombian context. Rev Esp Geriatr Gerontol. 2025;60(5):101657. doi: 10.1016/j.regg.2025.101657

 

  1. Mutai H, Obuchi K, Yokoi K, Furukawa T. Factors associated with health-related quality of life among community-dwelling older adults without social participation in Japan: A Cross-Sectional Study. J Appl Gerontol. 2025;44(6):893- 901. doi: 10.1177/07334648241290099

 

  1. Almeida VM, Carvalho C, Pereira MG. The contribution of purpose in life to psychological morbidity and quality of life in chronic pain patients. Psychol Health Med. 2020;25(2):160- 170. doi: 10.1080/13548506.2019.1665189

 

  1. Horii M, Hatta T, Hasegawa Y, et al. The association between health-Related quality of life and the meaning of life in community-dwelling older adults. BMC Geriatr. 2026;26:658. doi: 10.1186/s12877-026-07425-7

 

  1. Reed DE 2nd, Day MA, Ferreira-Valente A, Jensen MP. Belief in living a meaningful life and adjustment to chronic pain. Pain Med. 2025;26(1):30-38. doi: 10.1093/pm/pnae091

 

  1. Uki J, Mendoza T, Cleeland CS, Nakamura Y, Takeda F. A brief cancer pain assessment tool in Japanese: The utility of the Japanese Brief Pain Inventory-BPI-J. J Pain Symptom Manage. 1998;16(6):364-373. doi: 10.1016/s0885-3924(98)00098-0

 

  1. Matsuoka H, Sakano Y. Assessment of cognitive aspect of pain: Development, reliability, and validation of Japanese Version of Pain Catastrophizing Scale. Jpn J Psychosom Med. 2007;47(2):95-102. [In Japanese] doi: 10.15064/jjpm.47.2_95

 

  1. Steger MF, Frazier P, Oishi S, Kaler M. The meaning in life questionnaire: Assessing the presence of and search for meaning in life. J Couns Psychol. 2006;53(1):80-93. doi: 10.1037/0022-0167.53.1.80

 

  1. Steger MF, Kawabata Y, Shimai S, Otake K. The meaningful life in Japan and the United States: Levels and correlates of meaning in life. J Res Pers. 2008;42(3):660-678. doi: 10.1016/j.jrp.2007.09.003

 

  1. Fukuhara S, Ware JE, Kosinski M, Wada S, Gandek B. Psychometric and clinical tests of validity of the Japanese SF-36 Health Survey. J Clin Epidemiol. 1998;51(11):1045- 1053. doi: 10.1016/S0895-4356(98)00096-1

 

  1. Shimizu H. An introduction to the statistical free software HAD: Suggestions to improve teaching, learning and practice data analysis. J Media Informat Commun. 2016;1:59-73.

 

  1. Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39(2):175-191. doi: 10.3758/BF03193146

 

  1. Sutin AR, Luchetti M, Stephan Y, Sesker AA, Terracciano A. Purpose in life and stress: An individual-participant meta-analysis of 16 samples. J Affect Disord. 2024;345:378-385. doi: 10.1016/j.jad.2023.10.149

 

  1. Lewis NA, Hill PL. Sense of purpose in life and allostatic load in two longitudinal cohorts. J Psychosom Res. 2023;170:111346. doi: 10.1016/j.jpsychores.2023.111346

 

  1. Nie S, Peng H, Ju Q, et al. The relationship between meaning in life and health behaviors in adults aged 55 years and over during the COVID19 pandemic: the mediating role of risk perception and the moderating role of powerful others health locus of control. Int J Behav Med. 2023;30(3):388-397. doi: 10.1007/s12529-022-10100-x

 

  1. Wlazło M, Szlacheta P, Grajek M, et al. The impact of kinesiophobia on physical activity and quality of life in patients with chronic diseases: A systematic literature review. Appl Sci. 2025;15(4):2086. doi: 10.3390/app15042086

 

  1. Ranjbar S, Mazidi M, Sharpe L, Dehghani M, Khatibi A. Attentional control moderates the relationship between pain catastrophizing and selective attention to pain related stimuli. Sci Rep. 2020;10(1):12885. doi: 10.1038/s41598-020-69910-2

 

  1. Friedman NP, Robbins TW. The role of prefrontal cortex in cognitive control and executive function. Neuropsychopharmacology. 2022;47(1):72-89. doi: 10.1038/s41386-021-01132-0

 

  1. Romanella SM, Mencarelli L, Burke MJ, et al. Targeting neural correlates of placebo effects. Cogn Affect Behav Neurosci. 2023;23(2):217-236. doi: 10.3758/s13415-022-01039-3

 

  1. Lewis NA, Turiano NA, Payne BR, Hill PL. Purpose in life and cognitive functioning in adulthood. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2017;24(6):662-671. doi: 10.1080/13825585.2016.1251549

 

  1. Veinot J, Cane D, Hashmi JA. Low working memory underpins the association between aberrant functional properties of pain modulation circuitry and chronic back pain severity. J Pain. 2025;28:104795. doi: 10.1016/j.jpain.2025.104795

 

  1. Yang Y, Dong J, Qin P, et al. Impact of multimorbidity on health-related quality of life: the mediation role of intrinsic capacity - evidence from the WHO ICOPE pilot program in Lianyungang of China (2024). Arch Public Health. 2025;83(1):302. doi: 10.1186/s13690-025-01791-1

 

  1. Wilk M, Losińska K, Pripp AH, Korkosz M, Haugeberg G. Pain catastrophizing in rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis: Biopsychosocial perspective and impact on health-related quality of life. Rheumatol Int. 2022;42(4):669-682. doi: 10.1007/s00296-021-05070-4

 

  1. Alvarez-Astorga A, García-Azorín D, Hernández M, et al. Pain catastrophising in a population of patients with migraine. Neurología (Engl Ed). 2021;36(1):24-28. doi: 10.1016/j.nrl.2018.10.005
Share
Back to top
Health Psychology Research, Print ISSN: 2420-8124, Published by AccScience Publishing