Measuring health: related quality of life in hemodialysis patients. Psychometric properties of the Missoula VITAS Quality of Life Index (MVQOLI-15) in Greece

Different measuring tools have been used to understand the outcomes of end-stage renal dis ease (ESRD) therapies. However, survival, cost effectiveness and quality of life (QOL) are the main parameters to evaluate treatment of ESRD. The current study meant to assess the psycho metric properties (reliability and validity) of the Missoula-VITAS Quality of Life Index (MVQOLI 15) translation to Greek in patients undergoing hemodialysis (HD). A total sample of 79 HD patients voluntarily participated in this pilot study. Domain analysis of MVQOLI-15-Greek was conducted based on the collected data at ini tial assessment. The reliability properties of the instrument were tested using the following measures; internal consistency, repeatability, test-retest reliability and convergent validity. Domain analysis demonstrated that all domains of the questionnaire had good variability. MVQOLI-15-Greek internal consistency was sat isfactory with an overall Cronbach’s a at 0.74. Pearson’s r and intraclass correlation coefficient revealed strong correlations (ranging from 0.91 to 0.98) between initial assessment and re assessment. MVQOLI-15-Greek convergent validity analysis indicated that the domains were strongly related to the same construct. The find ings of the study indicate that the Greek version of MVQOLI-15 provided satisfactory psychomet ric properties supporting its use within patho logical populations and in the context of national QOL measurement.
1. Theofilou P. Outcome measurement in palliative care: quality of life. J AIDS Clinc Res 2012;3:1-6.
2. Apolone G, Mosconi P. Review of the concept of quality of life assessment and discussion of the present trend in clinical research. Nephrol Dial Transplant 1998;13:65-69.
3. Theofilou P. Self-reported functional status: an important predictor of mental health outcomes among chronic dialysis patients. Eur J Psychol Assess 2012;28:1-7.
4. Theofilou P. Association of insomnia with kidney disease quality of life reported by patients on maintenance dialysis. Psychol Health Med 2013;18:70-8.
5. Theofilou P. Medication adherence in Greek hemodialysis patients: the contribution of depression and health cognitions. Int J Behav Med 2012 Mar 10. [Epub ahead of print].
6. Joshi DV, Mooppil N, Lim FYJ. Validation of the kidney disease quality of life-short form: a cross-sectional study of a dialysis-targeted health measure in Singapore. BMC Nephrology 2010;11:36.
7. Cohen SR, Mount BM. Quality of life in terminal illness: defining and measuring the subjective well-being in the dying. J Palliat Care 1992;8:40-5.
8. Byock IR, Merriman MP. Measuring quality of life for patients with terminal illness: the Missoula-VITAS quality of life index. Palliat Med 1998;12:231-44.
9. Byock IR. The nature of suffering and the nature of opportunity at the end of life. Clin Geriatr Med 1996;12:237-52.
10. Theofilou P. Assessing heath-related quality of life using the Missoula - Vitas Quality Of Life Index (MVQOLI). J Clin Trials 2012;2:1-2.
11. Namisango E, Katabira E, Karamagi C, Baguma P. Validation of the Missoula-Vitas Quality of-Life Index among patients with advanced AIDS in Urban Kampala, Uganda. J Pain Symptom Manage 2007;33:189-202.
12. Guillemin F, Bombardier C, Beaton D. Cross cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. J Clin Epidemiol 1993;46:1417-32.
13. Bowden A, Fox-Rushby JA. A systematic and critical review of the process of translation and adaptation of generic health-related quality of life measures in Africa, Asia, Eastern Europe, the Middle East, South America. Soc Sci Med 2003;57:1289-306.
14. Hambleton RK. Issues, designs and technical guidelines for adapting tests into multiple languages and cultures. In: Hambleton RK, Merenda PF, Spielberger CD, eds. Adapting educational and psychological tests for cross-cultural assessment. London: Routledge; 2004. pp. 3-38.
15. Theofilou P, Kapsalis F, Panagiotaki H. Greek version of MVQOLI-15: translation and cultural adaptation. Int J Caring Sci 2012;5:289-94.
16. Red River College. Item analysis. Available from: http://xnet.rrc.mb.ca/tomh/item_analysis.htm. Accessed: 15 March 2012.
17. Trochim WMK. Types of reliability. Internal consistency. 2006. Available from: http://www.socialresearchmethods.net/kb/reltypes.php. Accessed: 19 March 2012.
18. Cronbach LJ, Shavelson RJ. My current thoughts on coefficient alpha and successor procedures. Educ Psychol Meas 2004;64:391-418.
19. Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrica 1951;16:297-334.
20. Nunnally JC. Psychometric theory. New York: McGraw-Hill; 1978.
21. Gliem JA, Gliem RR. Calculating, interpreting, and reporting Cronbach’s alpha reliability coefficient for likert-type scales. Available from: https://scholarworks.iupui.edu/bitstream/handle/1805/344/Gliem+&+Gliem.pdf?sequence=1.
22. Berg KE, Latin RW, eds. Measurements and data collection concepts. Essentials of research methods in health, physical education, exercise science, and recreation. 2nd edition. Baltimore-Philadelphia: Lippincott Williams & Wilkins, 2004; 165.
23. Fowler J, Jarvis P, Chevannes M. Practical statistics for nursing and health care. West Sussex, England: John Wiley & Sons, Ltd; 2002.
24. Shrout PE, Fleiss JL. Intraclass correlations: uses in assessing rater reliability. Psychol Bull 1979;86:420-8.
25. Dunn G, Everitt B. Clinical biostatistics: an introduction to evidence-based medicine. London: Edward Arnold, 1995.
26. Ottenbacher KJ, Tomchek SD. Reliability analysis in therapeutic research: practice and procedure. Am J Occup Ther 1992;47:10-6.
27. Portney L, Watkins M. Foundation of clinical research: applications to practice. Upper Saddle River: Prentice-Hall, 2000.
28. Web center for social research methods. Knowledge base. Convergent and discriminant validity. Available from: http://www.socialresearchmethods.net/kb/convdisc.php. Accessed: 18 March 2012.
29. Schwartz EC, Merriman PM, Reed G, Byock I. Evaluation of the Missoula-VITAS Quality of Life Index-revised: research tool or clinical tool? J Palliat Med 2005;8:121-35.